Lyons DE, Kumar P, Roan NR, Defechereux PA, Feschotte C, Lange UC, Murthy N, Sameshima P, Verdin E, Ake JA, Parsons MS, Nath A, Gianella S, Smith DM, Kallas EG, Villa TJ, Strange R, Mwesigwa B, Furler O’Brien RL, Nixon DF, Ndhlovu LC, Valente ST, Ott M.
2023 Oct 28;15(11):2171. doi: 10.3390/v15112171. PMID: 38005849; PMCID: PMC10674359.
Publication Category: HIV/AIDS
Comprehensive synergy mapping links a BAF- and NSL-containing “supercomplex” to the transcriptional silencing of HIV-1
Li Z, Deeks SG, Ott M, Greene WC.
2023 Sep 26;42(9):113055. doi: 10.1016/j.celrep.2023.113055. Epub 2023 Sep 7. PMID: 37682714; PMCID: PMC10591912.
The lysine methyltransferase SMYD5 amplifies HIV-1 transcription and is post-transcriptionally upregulated by Tat and USP11.
Boehm D, Lam V, Schnolzer M, Ott M.
2023 Mar 28;42(3):112234. doi: 10.1016/j.celrep.2023.112234. Epub 2023 Mar 9. PMID: 36897778; PMCID: PMC10124996.
Evaluating a New Class of AKT/mTOR Activators for HIV Latency Reversing Activity Ex Vivo and In Vivo.
Gramatica A, Schwarzer R, Brantley W, Varco-Merth B, Sperber HS, Hull PA, Montano M, Migueles SA, Rosenthal D, Hogan LE, Johnson JR, Packard TA, Grimmett ZW, Herzig E, Besnard E, Nekorchuk M, Hsiao F, Deeks SG, Snape M, Kiernan B, Roan NR, Lifson JD, Estes JD, Picker LJ, Verdin E, Krogan NJ, Henrich TJ, Connors M, Ott M, Pillai SK, Okoye AA, Greene WC.
doi: 10.1128/JVI.02393-20.
FOXO1 promotes HIV latency by suppressing ER stress in T cells.
Vallejo-Gracia A, Chen IP, Perrone R, et al. [published online ahead of print, 2020 Jun 15]. Nat Microbiol. 2020;10.1038/s41564-020-0742-9. doi:10.1038/s41564-020-0742-9
Turning up the heat on HIV-1.
Chen IP, Ott M. [published online ahead of print, 2020 Jun 30]. Proc Natl Acad Sci U S A. 2020;202010212. doi:10.1073/pnas.2010212117
A BAF’ling Approach to Curing HIV.
Tomar S, Ali I, Ott M. 2018
doi: 10.1016/j.chembiol.2018.12.007.
Host Methyltransferases and Demethylases: Potential New Epigenetic Targets for HIV Cure Strategies and Beyond.
Boehm D, Ott M.
doi: 10.1089/aid.2017.0180.
The Short Isoform of BRD4 Promotes HIV-1 Latency by Engaging Repressive SWI/SNF Chromatin-Remodeling Complexes.
Conrad RJ, Fozouni P, Thomas S, Sy H, Zhang Q, Zhou MM, Ott M.
Mol Cell. 2017 Aug 17. pii: S1097-2765(17)30549-X. doi: 10.1016/j.molcel.2017.07.025.
Flow Cytometric Analysis of HIV-1 Transcriptional Activity in Response to shRNA Knockdown in A2 and A72 J-Lat Cell Lines.
Boehm D, Ott M.
Bio Protoc. 2017 Jun 5;7(11):e2314. doi: 10.21769/BioProtoc.2314. PMID: 29082287; PMCID: PMC5659638.