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Publications

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Liu TY, Knott GJ, Smock DCJ, Desmarais JJ, Son S, Bhuiya A, Jakhanwal S, Prywes N, Agrawal S, Díaz de León Derby M, Switz NA, Armstrong M, Harris AR, Charles EJ, Thornton BW, Fozouni P, Shu J, Stephens SI, Kumar GR, Zhao C, Mok A, Iavarone AT, Escajeda AM, McIntosh ...
COVID-19 (SARS-CoV-2)
Biering SB, Van Dis E, Wehri E, Yamashiro LH, Nguyenla X, Dugast-Darzacq C, Graham TGW, Stroumza JR, Golovkine GR, Roberts AW, Fines DM, Spradlin JN, Ward CC, Bajaj T, Dovala D, Schulze-Gamen U, Bajaj R, Fox DM, Ott M, Murthy N, Nomura DK, Schaletzky J, Stanley SA. doi: 10.1021/acsinfecdis.1c00017.
Hepatitis
Vaishaali Natarajan, Camille R Simoneau, Ann L Erickson, Nathan L Meyers, Jody L Baron, Stewart Cooper, View ORCID ProfileTodd C McDevitt, Melanie Ott doi: https://doi.org/10.1101/2021.08.10.455738
COVID-19 (SARS-CoV-2)
Sungmin Son, Amy Lyden, Jeffrey Shu, Stephanie I. Stephens, Parinaz Fozouni, Gavin J. Knott, Dylan C. J. Smock, View ORCID ProfileTina Y. Liu, Daniela Boehm, Camille Simoneau, G. Renuka Kumar, View ORCID ProfileJennifer A. Doudna, Melanie Ott, View ORCID ProfileDaniel A. Fletcher doi: https://doi.org/10.1101/2021.08.02.21261509
COVID-19 (SARS-CoV-2)
Telwatte S, Kumar N, Vallejo-Gracia A, Kumar GR, Lu CM, Ott M, Wong JK, Yukl SA. doi: 10.1016/j.jviromet.2021.114115.
COVID-19 (SARS-CoV-2)
Deng X, Garcia-Knight MA, Khalid MM, Servellita V, Wang C, Morris MK, Sotomayor-González A, Glasner DR, Reyes KR, Gliwa AS, Reddy NP, Sanchez San Martin C, Federman S, Cheng J, Balcerek J, Taylor J, Streithorst JA, Miller S, Sreekumar B, Chen PY, Schulze-Gahmen U, Taha TY, Hayashi JM, Simoneau CR, ...
COVID-19 (SARS-CoV-2)
Le BL, Andreoletti G, Oskotsky T, Vallejo-Gracia A, Rosales R, Yu K, Kosti I, Leon KE, Bunis DG, Li C, Kumar GR, White KM, García-Sastre A, Ott M, Sirota M. doi: 10.1038/s41598-021-91625-1
COVID-19 (SARS-CoV-2)
Hysenaj L, Little S, Kulhanek K, Gbenedio OM, Rodriguez L, Shen A, Lone JC, Lupin-Jimenez LC, Bonser LR, Serwas NK, Bahl K, Mick E, Li JZ, Ding VW, Matsumoto S, Maishan M, Simoneau C, Fragiadakis G, Jablons DM, Langelier CR, Matthay M, Ott M, Krummel M, Combes AJ, Sil A, ...
COVID-19 (SARS-CoV-2)
Perez-Bermejo JA, Kang S, Rockwood SJ, Simoneau CR, Joy DA, Silva AC, Ramadoss GN, Flanigan WR, Fozouni P, Li H, Chen PY, Nakamura K, Whitman JD, Hanson PJ, McManus BM, Ott M, Conklin BR, McDevitt TC doi: 10.1126/scitranslmed.abf7872.
COVID-19 (SARS-CoV-2)
Weinberg ZY, Hilburger CE, Kim M, Cao L, Khalid M, Elmes S, Diwanji D, Hernandez E, Lopez J, Schaefer K, Smith AM, Zhou F; QCRG Structural Biology Consortium, Renuka Kumar G, Ott M, Baker D, El-Samad H. doi: 10.1101/2021.04.20.440678.
COVID-19 (SARS-CoV-2)
Telwatte S, Martin HA, Marczak R, Fozouni P, Vallejo-Gracia A, Kumar GR, Murray V, Lee S, Ott M, Wong JK, Yukl SA. doi: 10.1016/j.ymeth.2021.04.011.
Hepatitis
Kulsuptrakul J, Wang R, Meyers NL, Ott M, Puschnik AS. doi: 10.1016/j.celrep.2021.108859.
HIV/AIDS
Gramatica A, Schwarzer R, Brantley W, Varco-Merth B, Sperber HS, Hull PA, Montano M, Migueles SA, Rosenthal D, Hogan LE, Johnson JR, Packard TA, Grimmett ZW, Herzig E, Besnard E, Nekorchuk M, Hsiao F, Deeks SG, Snape M, Kiernan B, Roan NR, Lifson JD, Estes JD, Picker LJ, Verdin E, ...
COVID-19 (SARS-CoV-2)
Fozouni P, Son S, Díaz de León Derby M, Knott GJ, Gray CN, D’Ambrosio MV, Zhao C, Switz NA, Kumar GR, Stephens SI, Boehm D, Tsou CL, Shu J, Bhuiya A, Armstrong M, Harris AR, Chen PY, Osterloh JM, Meyer-Franke A, Joehnk B, Walcott K, Sil A, Langelier C, Pollard ...
COVID-19 (SARS-CoV-2)
Andrews MG, Mukhtar T, Eze UC, Simoneau CR, Perez Y, Mostajo-Radji MA, Wang S, Velmeshev D, Salma J, Kumar GR, Pollen AA, Crouch EE, Ott M, Kriegstein AR. doi: 10.1101/2021.01.17.427024.
COVID-19 (SARS-CoV-2)
Telwatte S, Kumar N, Vallejo-Gracia A, Kumar GR, Lu CM, Ott M, Wong JK, Yukl SA. doi: 10.1101/2021.01.12.425991.
COVID-19 (SARS-CoV-2)
Wang R, Simoneau CR, Kulsuptrakul J, Bouhaddou M, Travisano KA, Hayashi JM, Carlson-Stevermer J, Zengel JR, Richards CM, Fozouni P, Oki J, Rodriguez L, Joehnk B, Walcott K, Holden K, Sil A, Carette JE, Krogan NJ, Ott M, Puschnik AS. doi: 10.1016/j.cell.2020.12.004.
COVID-19 (SARS-CoV-2)
Schoof M, Faust B, Saunders RA, Sangwan S, Rezelj V, Hoppe N, Boone M, Billesbølle CB, Puchades C, Azumaya CM, Kratochvil HT, Zimanyi M, Deshpande I, Liang J, Dickinson S, Nguyen HC, Chio CM, Merz GE, Thompson MC, Diwanji D, Schaefer K, Anand AA, Dobzinski N, Zha BS, Simoneau CR, ...
Zika
Kristoffer Leon, Ryan Flynn, Mir M. Khalid, Krystal A. Fontaine, Tom Nguyen, G. Renuka Kumar, Camille R Simoneau, Sakshi Tomar, David Jimenez-Morales, Mariah Dunlap, Julia Kaye, Priya S Shah, Steven Finkbeiner, Nevan J Krogan, Carolyn Bertozzi, Jan E. Carette, Melanie Ott. doi: https://doi.org/10.1101/2020.12.03.410837
COVID-19 (SARS-CoV-2)
Samuel RM, Majd H, Richter MN, Ghazizadeh Z, Zekavat SM, Navickas A, Ramirez JT, Asgharian H, Simoneau CR, Bonser LR, Koh KD, Garcia-Knight M, Tassetto M, Sunshine S, Farahvashi S, Kalantari A, Liu W, Andino R, Zhao H, Natarajan P, Erle DJ, Ott M, Goodarzi H, Fattahi F. doi: 10.1016/j.stem.2020.11.009.
COVID-19 (SARS-CoV-2)
Simoneau CR, Ott M. doi: 10.1016/j.stem.2020.11.012.
Miao Y, Ha A, de Lau W, Yuki K, Santos AJM, You C, Geurts MH, Puschhof J, Pleguezuelos-Manzano C, Peng WC, Senlice R, Piani C, Buikema JW, Gbenedio OM, Vallon M, Yuan J, de Haan S, Hemrika W, Rösch K, Dang LT, Baker D, Ott M, Depeille P, Wu SM, ...
Covarrubias AJ, Kale A, Perrone R, Lopez-Dominguez JA, Pisco AO, Kasler HG, Schmidt MS, Heckenbach I, Kwok R, Wiley CD, Wong HS, Gibbs E, Iyer SS, Basisty N, Wu Q, Kim IJ, Silva E, Vitangcol K, Shin KO, Lee YM, Riley R, Ben-Sahra I, Ott M, Schilling B, Scheibye-Knudsen M, ...
Xu C, Wang L, Fozouni P, Evjen G, Chandra V, Jiang J, Lu C, Nicastri M, Bretz C, Winkler JD, Amaravadi R, Garcia BA, Adams PD, Ott M, Tong W, Johansen T, Dou Z, Berger SL. doi: 10.1038/s41556-020-00579-5.
COVID-19 (SARS-CoV-2)
Wang R, Simoneau CR, Kulsuptrakul J, Bouhaddou M, Travisano K, Hayashi JM, Carlson-Stevermer J, Oki J, Holden K, Krogan NJ, Ott M, Puschnik AS. doi: 10.1101/2020.09.24.312298.
COVID-19 (SARS-CoV-2)
Pérez-Bermejo JA, Kang S, Rockwood SJ, Simoneau CR, Joy DA, Ramadoss GN, Silva AC, Flanigan WR, Li H, Nakamura K, Whitman JD, Ott M, Conklin BR, McDevitt TC. doi: 10.1101/2020.08.25.265561.
COVID-19 (SARS-CoV-2)
Bouhaddou M, Memon D, Meyer B, …, Swaney DL, Beltrao P, Krogan NJ   Cell. 2020. Epub 2020/07/10. doi: 10.1016/j.cell.2020.06.034. PubMed PMID: 32645325; PMCID: PMC7321036.
HIV/AIDS
Chen IP, Ott M.  [published online ahead of print, 2020 Jun 30].  Proc Natl Acad Sci U S A. 2020;202010212. doi:10.1073/pnas.2010212117
HIV/AIDS
Vallejo-Gracia A, Chen IP, Perrone R, et al.   [published online ahead of print, 2020 Jun 15]. Nat Microbiol. 2020;10.1038/s41564-020-0742-9. doi:10.1038/s41564-020-0742-9
Leon K, Ott M.   Semin Cell Dev Biol. 2020;S1084-9521(19)30189-2. doi:10.1016/j.semcdb.2020.05.018
Lyons DE, McMahon S, Ott M.   2020;11(2):66-82. doi:10.1080/21541264.2020.1762468
COVID-19 (SARS-CoV-2)
Gordon DE, Jang GM, et al (2020) A   Nature. 2020. Epub 2020/05/01. doi: 10.1038/s41586-020-2286-9. PubMed PMID: 32353859.
Zika
Khan S, Lew I, Wu F, Fritts L, Fontaine KA, Tomar S, Trapecar M, Shehata HM, Ott M, Miller C, Sanjabi S (2019)   Nat Commun. 2019 Sep 25;10(1):4344. doi: 10.1038/s41467-019-12371-7.
Schilling B, Meyer JG, Wei L, Ott M, Verdin E. DOI: 10.1007/978-1-4939-9434-2_1.
HIV/AIDS
Tomar S, Ali I, Ott M. 2018 doi: 10.1016/j.chembiol.2018.12.007.
Zika
Fontaine KA, Leon KE, Khalid MM, Tomar S, Jimenez-Morales D, Dunlap M, Kaye JA, Shah PS, Finkbeiner S, Krogan NJ, Ott M. doi: 10.1128/mBio.02126-18.
Ali I, Ruiz DG, Ni Z, Johnson JR, Zhang H, Li PC, Conrad RJ, Guo X, Min J, Greenblatt J, Jacobson M, Krogan NJ, Ott M. 2018.  bioRxiv 442491; doi: https://doi.org/10.1101/442491.
Chemical Reviews
Ali, I., Conrad, R. J., Veridin, E., Ott, M., 2018. Chem. Rev., 118(3), pp.1216–1252.
Jeng, M.Y., Hull, P.A., Fei, M., Kwon, H.-S., Tsou, C.-L., Kasler, H., Ng, C.-P., Gordon, D.E., Johnson, J., Krogan, N., Verdin, E., Ott, M. doi: 10.1084/jem.20161066. in the press: Medical Xpress
HIV/AIDS
Conrad RJ, Fozouni P, Thomas S, Sy H, Zhang Q, Zhou MM, Ott M. Mol Cell. 2017 Aug 17. pii: S1097-2765(17)30549-X. doi: 10.1016/j.molcel.2017.07.025.
HIV/AIDS
Boehm D, Ott M. Bio Protoc. 2017 May 20;7(10). pii: e2290. doi: 10.21769/BioProtoc.2290.
HIV/AIDS
Boehm D, Jeng M, Camus G, Gramatica A, Schwarzer R, Johnson JR, Hull PA, Montano M, Sakane N, Pagans S, Godin R, Deeks SG, Krogan NJ, Greene WC, Ott M. Cell Host Microbe. 2017 May 10;21(5):569-579.e6.
Ali I, Conrad R, Ott M (2016) Cell Host Microbe.
Zika
Khan S, Woodruff EM, Trapecar M, Fontaine KA, Ezaki A, Borbet TC, Ott M, Sanjabi S. (2016) J Exp Med
Besnard E, Hakre S, Kampmann M, Lim HW, Hosmane NN, Martin A, Bassik MC, Verschueren E, Battivelli E, Chan J, STevensson JP, Gramatica A, Conrad R, Ott M, Greene WC, Krogan NJ, Siliciano RF, Weissman JS, Verdin E (2016). Cell Host Microbe.
HIV/AIDS
Deeks SG, Lewin SR, Ross AL, Ananworanich J, Benkirane M, Cannon P, Chomont N, Douek D, Lifson JD, Lo YR, Kuritzkes D, Margolis D, Mellors J, Persaud D, Tucker JD, Barre-Sinoussi F; International AIDS Society Towards a Cure Working Group, Alter G, Auerbach J, Autran B, Barouch DH, Behrens G, ...
HIV/AIDS
Ali I, Ramage H, Boehm D, Dirk LMA, Sakane N, Hanada, K, Pagans S, Kaehlcke K, Aull K, Weinberger L, Trievel R, Schnoelzer M, Kamada M, Houtz R, Ott M. (2016) J Biol Chem.
Shirakawa K, Wang L, Man N, Maksimoska J,Sorum AW, Lim HW, Lee IS, Shimazu T, Newman JC, Schröder S, Ott M, Marmorstein R, Meier J, Nimer S, Verdin E (2016) Elife
HIV/AIDS
Conrad RJ, Ott M (2016)   ACS Chem Biol
Rosenkranz E, Metz CHD, Maywald M, Hilgers RD, Wessels I, Senff T, Haase H, Jaeger M, Ott M, Aspinall R, Pumaekers B, Rink L. (2016) Mol Nutr Food Res
HIV/AIDS
Jeng MY, Ali I, Ott M (2015).  Crit Rev Biochem Mol Bio 50:314-325.
Lim HW, Kang SG, Ryu JK, Schilling B, Fei M, Lee IS, Kehasse A, Shirakawa K, Yokoyama M, Schnolzer M, Kasler HG, Kwon H-S, Gibson BW, Sato H, Akassoglou K, Xiao C, Littman DR, Ott M, Verdin E (2015).  J Exp Med 212:973
Simonti CN, Pollard KS, Schröder S, He D, Bruneau BG, Ott M, Capra JA (2015).  BMC Evol Biol 15:35
Hepatitis
Ramage HR, Kumar GR, Verschueren E, Johnson JR, Von Dollen J, Johnson T, Newton B, Shah P, Horner J, Krogan NJ, Ott M. doi: 10.1016/j.molcel.2014.12.028.
Hepatitis
Camus G, Schweiger M, Herker E, Harris C, Kondratowicz AS, Tsou C-L, Farese RV, Herath K, Previs SF, Roddy TP, Pinto S, Zechner R, Ott M (2014). J Biol Chem
Schröder S, Herker E, Itzen F, He D, Thomas S, Gilchrist DA, Kaehlcke K, Cho S, Pollard KS, Capra JA, Schnolzer M, Cole PA, Geyer M, Bruneau BG, Adelman K, Ott M (2013).  Mol Cell 52:314–324.
HIV/AIDS
Boehm D, Conrad R, Ott M (2013).  Viruses 5:1571–1586. doi: 10.3390/v5061571
Camus G, Ott M (2013).  Nat Med 19:671–672.
HIV/AIDS
Ott M, Verdin E (2013).  Cell Host Microbe 13:625–626.
Hepatitis
Vogt DA, Camus G, Herker E, Webster BR, Tsou C-L, Greene WC, Yen T-SB, Ott M (2013).  PLoS Pathog 9:e1003302.
Hepatitis
Camus G, Herker E, Modi AA, Haas JT, Ramage HR, Farese RV, Ott M (2013). J Biol Chem 288:9915–9923.
HIV/AIDS
Boehm D, Calvanese V, Dar RD, Xing S, Schroeder S, Martins L, Aull K, Li P-C, Planelles V, Bradner JE, Zhou M-M, Siliciano RF, Weinberger L, Verdin E, Ott M (2013). Cell Cycle 12:452–462.
Knipe DM, Lieberman PM, Jung JU, McBride AA, Morris KV, Ott M, Margolis D, Nieto A, Nevels M, Parks RJ, Kristie TM (2013). Virology 435:141–156.
Camus G, Vogt DA, Kondratowicz AS, Ott M (2013).  Methods Cell Biol 116:167–190.
Hepatitis
Webster B, Wissing S, Herker E, Ott M, Greene WC (2013).  J Virol 87:581–596.
Kwon HS, Lim HW, Wu J, Schnolzer M, Verdin E, Ott M (2012). J Immunol 188:2712–2721.
Herker E, Ott M (2012).  J Biol Chem 287:2280–2287.
Schröder S, Cho S, Zeng L, Zhang Q, Kaehlcke K, Mak L, Lau J, Bisgrove D, Schnolzer M, Verdin E, Zhou M-M, Ott M (2012).  J Biol Chem 287:1090–1099.
Hepatitis
Harris C, Herker E, Farese RV, Ott M (2011).  J Biol Chem 286:42615–42625.
HIV/AIDS
Ott M, Geyer M, Zhou Q (2011).  Cell Host Microbe 10:426–435.
HIV/AIDS
Sakane N, Kwon H-S, Pagans S, Kaehlcke K, Mizusawa Y, Kamada M, Lassen KG, Chan J, Greene WC, Schnoelzer M, Ott M (2011). PLoS Pathog 7:e1002184.
Hepatitis
Herker E, Ott M (2011).  Trends Endocrinol Metab 22:241–248.
HIV/AIDS
Pagans S, Sakane N, Schnolzer M, Ott M (2011). Methods 53:91–96.
Hepatitis
Herker E, Harris C, Hernandez C, Carpentier A, Kaehlcke K, Rosenberg AR, Farese RV, Ott M (2010). Nat Med 16:1295–1298.
Min S-W, Cho S-H, Zhou Y, Schroeder S, Haroutunian V, Seeley WW, Huang EJ, Shen Y, Masliah E, Mukherjee C, Meyers D, Cole PA, Ott M, Gan L (2010). Neuron 67:953–966.
Ott M, Verdin E (2010). Chem Biol 17:417–418.
Cho S, Schroeder S, Kaehlcke K, Kwon H-S, Pedal A, Herker E, Schnoelzer M, Ott M (2009). EMBO J 28:1407–1417.
HIV/AIDS
Pagans S, Kauder SE, Kaehlcke K, Sakane N, Schroeder S, Dormeyer W, Trievel RC, Verdin E, Schnolzer M, Ott M (2010). Cell Host Microbe 7:234–244.
HIV/AIDS
Ott M, Dorr A, Hetzer-Egger C, Kaehlcke K, Schnolzer M, Henklein P, Cole P, Zhou M-M, Verdin E (2004). Novartis Found Symp 259:182–93– discussion 193–6– 223–5.
Nakamura K, Nemani VM, Wallender EK, Kaehlcke K, Ott M, Edwards RH (2008). J Neurosci 28:12305–12317.
Kwon H-S, Ott M (2008). Trends Biochem Sci 33:517–525.
Kwon H-S, Brent MM, Getachew R, Jayakumar P, Chen L-F, Schnolzer M, McBurney MW, Marmorstein R, Greene WC, Ott M (2008). Cell Host Microbe 3:158–167.
HIV/AIDS
Hetzer C, Bisgrove D, Cohen MS, Pedal A, Kaehlcke K, Speyerer A, Bartscherer K, Taunton J, Ott M (2007). PLoS ONE 2:e151.
Hepatitis
Nieters A, Kallinowski B, Brennan P, Ott M, Maynadié M, Benavente Y, Foretova L, Cocco PL, Staines A, Vornanen M, Whitby D, Boffetta P, Becker N, De Sanjosé S (2006). Gastroenterology 131:1879–1886.
HIV/AIDS
Mahmoudi T, Parra M, Vries RGJ, Kauder SE, Verrijzer CP, Ott M, Verdin E (2006). J Biol Chem 281:19960–19968.
Dormeyer W, Ott M, Schnolzer M (2005). Methods 36:376–382.
HIV/AIDS
Hetzer C, Dormeyer W, Schnolzer M, Ott M (2005). Microbes Infect 7:1364–1369.
HIV/AIDS
Pagans S, Pedal A, North BJ, Kaehlcke K, Marshall BL, Dorr A, Hetzer-Egger C, Henklein P, Frye R, McBurney MW, Hruby H, Jung M, Verdin E, Ott M (2005). Plos Biol 3:e41.
Hepatitis
Schwer B, Ren S, Pietschmann T, Kartenbeck J, Kaehlcke K, Bartenschlager R, Yen TSB, Ott M (2004). J Virol 78:7958–7968.
HIV/AIDS
Witte V, Laffert B, Rosorius O, Lischka P, Blume K, Galler G, Stilper A, Willbold D, D’Aloja P, Sixt M, Kolanus J, Ott M, Kolanus W, Schuler G, Baur AS (2004). Mol Cell 13:179–190.
HIV/AIDS
Kaehlcke K, Dorr A, Hetzer-Egger C, Kiermer V, Henklein P, Schnoelzer M, Loret E, Cole PA, Verdin E, Ott M (2003). Mol Cell 12:167–176.
HIV/AIDS
Dormeyer W, Dorr A, Ott M, Schnolzer M (2003). Anal Bioanal Chem 376:994–1005.
Fritzsching B, Schwer B, Kartenbeck J, Pedal A, Horejsi V, Ott M (2002). J Immunol 169:5531–5537.
Dorr A, Kiermer V, Pedal A, Rackwitz H-R, Henklein P, Schubert U, Zhou M-M, Verdin E, Ott M (2002). EMBO J 21:2715–2723.
HIV/AIDS
Mujtaba S, He Y, Zeng L, Farooq A, Carlson JE, Ott M, Verdin E, Zhou M-M (2002). Mol Cell 9:575–586.
HIV/AIDS
Ott M, Schnolzer M, Garnica J, Fischle W, Emiliani S (1999). Curr Biol 9:1489-92.
HIV/AIDS
Ott M, Emiliani S, Van Lint C, Herbein G, Lovett J (1997). Science 275:1481-5.
HIV/AIDS
McCloskey TW, Ott M, Tribble E, Khan SA, Teichberg S, Paul MO, Pahwa S, Verdin E, Chirmule N (1997). J. Immunol 158:1014-9.
HIV/AIDS
Emiliani S, Van Lint C, Fischle W, Paras P, Ott M, Brady J, Verdin E (1996). Proc Natl Acad Sci U S A 93:6377-81.
COVID-19 (SARS-CoV-2)
Gordon DE, Hiatt J, Bouhaddou M, Rezelj VV, Ulferts S, Braberg H, Jureka AS, Obernier K, Guo JZ, Batra J, Kaake RM, Weckstein AR, Owens TW, Gupta M, Pourmal S, Titus EW, Cakir M, Soucheray M, McGregor M, Cakir Z, Jang G, O’Meara MJ, Tummino TA, Zhang Z, Foussard H, ...