Ott Lab News

Gladstone Institutes — To spread between cells in the body and hop from person to person, human immunodeficiency virus (HIV) must copy its genetic material, produce viral proteins, and assemble new virus particles. For this complex process to occur, a viral protein called Tat must bind to a section of the virus’s RNA—the ...

When Zika virus crosses the placenta to infect a foetus in a pregnant woman, it attacks life before it’s had a chance to establish itself, like squashing a seed before planting it. In particular, the virus infects starter cells for the nervous system, neural progenitor cells, thus causing wide-reaching developmental ...

The Atlantic — This year’s might include XBB.1 and … perhaps no other strain. This fall, millions of Americans might be lining up for yet another kind of COVID vaccine: their first-ever dose that lacks the strain that ignited the pandemic more than three and a half years ago. Unlike the current, bivalent ...

Yahoo Finance — InvisiShield Technologies Ltd., a pre-clinical-stage biotechnology company focused on developing intranasal preventives for major disease-causing respiratory viruses, today announced a collaboration with Gladstone Institutes to develop intranasal preventatives against airborne infection, including SARS-CoV-2, influenza, and respiratory syncytial virus (RSV). Gladstone Institutes, a non-profit biomedical research organization that uses visionary science ...

Gladstone Institutes — As we approach the height of the holiday season, some medical experts have warned of a potential “tripledemic”—a simultaneous surge in cases of COVID-19, the flu, and RSV (respiratory syncytial virus). How concerned should you be, and what does this mean for your holiday plans? We asked three Gladstone virologists—Senior ...

Nob Hill Gazette — When California shut down in March 2020 and many San Franciscans stayed at home, obsessively ordering hand sanitizer, a group of local scientists pivoted from the projects they were working on and poured all their energy into COVID-19. Jennifer Doudna, PhD, and Melanie Ott, MD, PhD, developed a new testing ...