Li Z, Ott M. HIV-induced T cell quiescence and the origins of viral latency. Nat Immunol. 2025 Oct;26(10):1633-1634. doi: 10.1038/s41590-025-02282-9. PMID: 41006602.
Publication Category: HIV/AIDS
Epigenetic Functions of SMYD5 and Its Role in Development, Cancer and Other Cellular Processes
Boehm, D., Khanna, K., Li, Z., & Ott, M. (2026). Epigenetic Functions of SMYD5 and Its Role in Development, Cancer and Other Cellular Processes. International Journal of Molecular Sciences, 27(13), 5884. https://doi.org/10.3390/ijms27135884
Self-Dimerization Induced Proximity Targeting Chimeras (SDIPTAC) Lead to DCAF1 Loss of Function and Inhibition of HIV Replication
Mabanglo MF, Srivastava S, Matsui Y, Li Z, Noureldin M, Pogmore JP, Hoffer L, Taherian F, Hajian T, Tucker S, Mamai A, Kiyota T, Aman A, Al-Awar R, Marcellus R, Uehling DE, Ott M, Ramnauth J, Vedadi M.
doi: 10.1021/acs.jmedchem.6c00126. Epub ahead of print. PMID: 42150007.
Multiomic analysis of ART-interruption cohorts identifies cell-extrinsic and -intrinsic mechanisms driving lymphocyte-mediated control of HIV rebound.
Ma T, George AF, Li Z, Thomas R, Yin K, Shin MG, Montano M, Matsui Y, Ashokkumar M, Young K, Prigann J, Frouard J, Leddy S, Adiba M, Herrde C, Lange UC, Feschotte C, Nixon DF, Browne EP, Archin NM, Li JZ, Smith D, Deeks S, Søgaard OS, Tolstrup M, Lee S, Pillai SK, Abdel-Mohsen M, Pollard KS, Siliciano R, Ott M, Greene WC, Roan NR.
Immunity. 2026 Mar 20:S1074-7613(26)00049-X. doi: 10.1016/j.immuni.2026.01.029. Epub ahead of print. PMID: 41864210.
Meeting Summary for Keystone Symposia on HIV Cure: Antiretroviral Therapy (ART)-Free Control of HIV Infection in Durban, South Africa, 2025
Tanaka, K., Chikowore, T. J. B., Deeks, S. G., Estes, J. D., Ho, Y. C., Jiang, S., Lee, M. J., Li, C., Machinda, A., Martins, M., Mdletshe, P., Ndhlovu, Z. M., Neogi, U., Ott, M. M., Rasmussen, T. A., Reddy, K., Rutishauser, R. L., Farrell-Sherman, A., Tiemessen, C. T., Voss, J. E., … McCune, J. M. (2025).
Pathogens & immunity, 10(2), 196–229. https://doi.org/10.20411/pai.v10i2.885
HIV-induced T cell quiescence and the origins of viral latency
Li Z, Ott M.
2025 Oct;26(10):1633-1634. doi: 10.1038/s41590-025-02282-9. PMID: 41006602.
Silencing the transcriptionally active HIV reservoir to improve treatment outcomes.
Prigann J, Tavora R, Furler O’Brien RL, Schulze-Gahmen U, Boehm D, Roan NR, Nixon DF, Ndhlovu LC, Valente S, Ott M.
2024 Oct;9(10):2470-2472. doi: 10.1038/s41564-024-01816-5. PMID: 39289508.
CRISPR-Cas9 screen of E3 ubiquitin ligases identifies TRAF2 and UHRF1 as regulators of HIV latency in primary human T cells.
Rathore U, Haas P, Easwar Kumar V, Hiatt J, Haas KM, Bouhaddou M, Swaney DL, Stevenson E, Zuliani-Alvarez L, McGregor MJ, Turner-Groth A, Ochieng’ Olwal C, Bediako Y, Braberg H, Soucheray M, Ott M, Eckhardt M, Hultquist JF, Marson A, Kaake RM, Krogan NJ.
2024 Feb 27:e0222223. doi: 10.1128/mbio.02222-23. Epub ahead of print. PMID: 38411080.
Protocol for an in vitro assay to study HIV-1 Tat methylation
Boehm D, Kaehlcke K, Schnoelzer M, Ott M.
2023 Nov 17;4(4):102687. doi: 10.1016/j.xpro.2023.102687. Epub ahead of print. PMID: 37979180.
A flow cytometry-based assay to investigate HIV-1 expression in SMYD5 shRNA containing primary CD4+ T cells
Boehm D, Ott M.
STAR Protoc. 2023 Nov 4;4(4):102694. doi: 10.1016/j.xpro.2023.102694. Epub ahead of print. PMID: 37925635.