Publications Archive : Page 2 of 18 : The Ott Lab

Fibrin drives thromboinflammation and neuropathology in COVID-19.

Ryu JK, Yan Z, Montano M, Sozmen EG, Dixit K, Suryawanshi RK, Matsui Y, Helmy E, Kaushal P, Makanani SK, Deerinck TJ, Meyer-Franke A, Rios Coronado PE, Trevino TN, Shin MG, Tognatta R, Liu Y, Schuck R, Le L, Miyajima H, Mendiola AS, Arun N, Guo B, Taha TY, Agrawal A, MacDonald E, Aries O, Yan A, Weaver O, Petersen MA, Meza Acevedo R, Alzamora MDPS, Thomas R, Traglia M, Kouznetsova VL, Tsigelny IF, Pico AR, Red-Horse K, Ellisman MH, Krogan NJ, Bouhaddou M, Ott M, Greene WC, Akassoglou K.

2024 Sep;633(8031):905-913. doi: 10.1038/s41586-024-07873-4. Epub 2024 Aug 28. PMID: 39198643; PMCID: PMC11424477.

Understanding emerging and re-emerging viruses to facilitate pandemic preparedness.

Zapatero-Belinchón FJ, Kumar P, Ott M, Schwartz O, Sigal A.

2024 Sep;9(9):2208-2211. doi: 10.1038/s41564-024-01789-5. PMID: 39198691.

Neutralizing and binding antibody responses to SARS-CoV-2 with hybrid immunity in pregnancy.

Li L, Matsui Y, Prahl MK, Cassidy AG, Golan Y, Jigmeddagva U, Ozarslan N, Lin CY, Buarpung S, Gonzalez VJ, Chidboy MA, Basilio E, Lynch KL, Song D, Jegatheesan P, Rai DS, Govindaswami B, Needens J, Rincon M, Myatt L, Taha TY, Montano M, Ott M, Greene WC, Gaw SL.

2024 Aug 27;9(1):156. doi: 10.1038/s41541-024-00948-3. PMID: 39191763; PMCID: PMC11349990.

Immediate myeloid depot for SARS-CoV-2 in the human lung.

Magnen M, You R, Rao AA, Davis RT, Rodriguez L, Bernard O, Simoneau CR, Hysenaj L, Hu KH, Maishan M, Conrad C, Gbenedio OM, Samad B, Consortium TUC, Love C, Woodruff PG, Erle DJ, Hendrickson CM, Calfee CS, Matthay MA, Roose JP, Sil A, Ott M, Langelier CR, Krummel MF, Looney MR.

2024 Aug 2;10(31):eadm8836. doi: 10.1126/sciadv.adm8836. Epub 2024 Jul 31. PMID: 39083602; PMCID: PMC11290487.

NF-κB inhibitor alpha controls SARS-CoV-2 infection in ACE2-overexpressing human airway organoids.

Simoneau CR, Chen PY, Xing GK, Hayashi JM, Chen IP, Khalid MM, Meyers NL, Taha TY, Leon KE, Suryawanshi RK, McCavitt-Malvido M, Ashuach T, Fontaine KA, Rodriguez L, Joehnk B, Walcott K, Vasudevan S, Fang X, Maishan M, Schultz S, Roose JP, Matthay MA, Sil A, Arjomandi M, Yosef N, Ott M.

14(1):15351. doi: 10.1038/s41598-024-66003-2. PMID: 38961189; PMCID: PMC11222426.

Assembly reactions of SARS-CoV-2 nucleocapsid protein with nucleic acid

Zhao H, Syed AM, Khalid MM, Nguyen A, Ciling A, Wu D, Yau WM, Srinivasan S, Esposito D, Doudna JA, Piszczek G, Ott M, Schuck P.
2024 Jun 24;52(11):6647-6661. doi: 10.1093/nar/gkae256. PMID: 38587193; PMCID: PMC11194069.

Colloidal aggregation confounds cell-based Covid-19 antiviral screens

Glenn IS, Hall LN, Khalid MM, Ott M, Shoichet BK.

2024 Jun 12. doi: 10.1021/acs.jmedchem.4c00597. Epub ahead of print. PMID: 38864383.

CRISPR-Cas9 screen of E3 ubiquitin ligases identifies TRAF2 and UHRF1 as regulators of HIV latency in primary human T cells.

Rathore U, Haas P, Easwar Kumar V, Hiatt J, Haas KM, Bouhaddou M, Swaney DL, Stevenson E, Zuliani-Alvarez L, McGregor MJ, Turner-Groth A, Ochieng’ Olwal C, Bediako Y, Braberg H, Soucheray M, Ott M, Eckhardt M, Hultquist JF, Marson A, Kaake RM, Krogan NJ.
2024 Feb 27:e0222223. doi: 10.1128/mbio.02222-23. Epub ahead of print. PMID: 38411080.

De novo-designed minibinders expand the synthetic biology sensing repertoire

Weinberg ZY, Soliman SS, Kim MS, Chen IP, Ott M, El-Samad H.

2024 Jan 15:2024.01.12.575267. doi: 10.1101/2024.01.12.575267. PMID: 38293112; PMCID: PMC10827046.

Previous exposure to Spike-providing parental strains confers neutralizing immunity to XBB lineage and other SARS-CoV-2 recombinants in the context of vaccination

Suryawanshi RK, Taha TY, McCavitt-Malvido M, Silva I, Khalid MM, Syed AM, Chen IP, Saldhi P, Sreekumar B, Montano M, Foresythe K, Tabata T, Kumar GR, Sotomayor-Gonzalez A, Servellita V, Gliwa A, Nguyen J, Kojima N, Arellanor T, Bussanich A, Hess V, Shacreaw M, Lopez L, Brobeck M, Turner F, Wang Y, Ghazarian S, Davis G, Rodriguez D, Doudna J, Spraggon L, Chiu CY, Ott M.
2023 Dec;12(2):2270071. doi: 10.1080/22221751.2023.2270071. Epub 2023 Oct 31. PMID: 37869789; PMCID: PMC10619466.

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