Ott M, Schwartz O, Sigal A.
646(8083):31-34. doi: 10.1038/d41586-025-03151-z. PMID: 41023166.
Archives: Publications
Publications
HIV-induced T cell quiescence and the origins of viral latency
Li Z, Ott M.
2025 Oct;26(10):1633-1634. doi: 10.1038/s41590-025-02282-9. PMID: 41006602.
Neuroendocrine cells orchestrate regeneration through Desert hedgehog signaling
Kong W, Lu WJ, Dubey M, Suryawanshi RK, Vijayakumar S, Jeong Y, Gombar S, Diehn M, Shin K, Ott M, Chien YH, Sarin KY, Desai TJ, Beachy PA.
188(18):5020-5038.e20. doi: 10.1016/j.cell.2025.05.012. Epub 2025 Jun 9. PMID: 40494346; PMCID: PMC12232213.
Coronavirus protein interaction mapping in bat and human cells identifies molecular and genetic switches for immune evasion and replication
Batra J, Rutkowska M, Zhou Y, Ye C, Adavikolanu R, Young JM, Anand D, Verma S, Gordon M, Malpotra S, Cupic A, Kehrer T, Moen JM, Winters DM, Rojc A, Mena I, Aslam S, Martinez-Romero C, Conde Viñas I, Khalil Z, Farrugia K, Banerjee A, Tussia-Cohen D, Santos MD, Maji S, Muralidharan M, Foussard H, Chen IP, Fuchs R, Felipe CS, Zuliani-Alvarez L, Choudhury P, Obernier K, Gracias S, Suryawanshi R, Ibáñez C, Juste J, Pache L, Taha TY, Jouvenet N, Verba KA, Fraser JS, Demeret C, Stroud RM, van Bakel H, Ott M, Hagai T, Polacco B, Swaney DL, Echeverria I, Bouhaddou M, Eckhardt M, Malik HS, Martinez-Sobrido L, Miorin L, García-Sastre A, Krogan NJ.
bioRxiv [Preprint]. 2025 Jul 28:2025.07.26.666918. doi: 10.1101/2025.07.26.666918. PMID: 40766693; PMCID: PMC12324264.
Programmable translational inhibition by a molecular glue-oligonucleotide conjugate
Wang S, Kovalski JR, Zapatero-Belinchón FJ, Bennett M, Kuzuoglu-Öztürk D, Li Q, Stevenson E, Liu J, Krogan NJ, Ott M, Swaney DL, Ruggero D, Lou K, Shokat KM. bioRxiv [Preprint]. 2025 Jul 16:2025.07.15.664547. doi: 10.1101/2025.07.15.664547. PMID: 40791481; PMCID: PMC12338673.
Neuroendocrine cells orchestrate regeneration through Desert hedgehog signaling
Kong W, Lu WJ, Dubey M, Suryawanshi RK, Vijayakumar S, Jeong Y, Gombar S, Diehn M, Shin K, Ott M, Chien YH, Sarin KY, Desai TJ, Beachy PA.
2025 Jun 3:S0092-8674(25)00562-8. doi: 10.1016/j.cell.2025.05.012. Epub ahead of print. PMID: 40494346.
A non-spike nucleocapsid R204P mutation in SARS-CoV-2 Omicron XEC enhances inflammation and pathogenicity
Tsujino S, Tsuda M, Ito J, Deguchi S, Taha TY, Nasser H, Wang L, Rosecrans J, Suzuki R, Suzuki S, Yoshimatsu K, Ott M; Genotype to Phenotype Japan (G2P-Japan) Consortium; Ikeda T, Takayama K, Sato K, Tanaka S, Tamura T, Fukuhara T.
2025 May 30:2025.05.28.656516. doi: 10.1101/2025.05.28.656516. PMID: 40502047; PMCID: PMC12154822.
Structure-based discovery of highly bioavailable, covalent, broad-spectrum coronavirus MPro inhibitors with potent in vivo efficacy
Detomasi TC, Degotte G, Huang S, Suryawanshi RK, Diallo A, Lizzadro L, Zapatero-Belinchón FJ, Taha TY, Li J, Richards AL, Hantz ER, Alam Z, Montano M, McCavitt-Malvido M, Gumpena R, Partridge JR, Correy GJ, Matsui Y, Charvat AF, Glenn IS, Rosecrans J, Revalde JL, Anderson D, Hultquist JF, Arkin MR, Neitz RJ, Swaney DL, Krogan NJ, Shoichet BK, Verba KA, Ott M, Renslo AR, Craik CS.
2025 Apr 25;11(17):eadt7836. doi: 10.1126/sciadv.adt7836. Epub 2025 Apr 23. PMID: 40267184; PMCID: PMC12017303.
Enhanced RNA replication and pathogenesis in recent SARS-CoV-2 variants harboring the L260F mutation in NSP6
Taha TY, Ezzatpour S, Hayashi JM, Ye C, Zapatero-Belinchón FJ, Rosecrans JA, Kimmerly GR, Chen IP, Walcott K, Kurianowicz A, Jorgens DM, Chaplin NR, Choi A, Buchholz DW, Sahler J, Hilt ZT, Imbiakha B, Vagi-Szmola C, Montano M, Stevenson E, Gordon M, Swaney DL, Krogan NJ, Whittaker GR, Martinez-Sobrido L, Aguilar HC, Ott M.
2025 Mar 31;21(3):e1013020. doi: 10.1371/journal.ppat.1013020. PMID: 40163530; PMCID: PMC11981139.
Torsional twist of the SARS-CoV and SARS-CoV-2 SUD-N and SUD-M domains
Rosas-Lemus M, Minasov G, Brunzelle JS, Taha TY, Lemak S, Yin S, Shuvalova L, Rosecrans J, Khanna K, Seifert HS, Savchenko A, Stogios PJ, Ott M, Satchell KJF.
2025 Mar;34(3):e70050. doi: 10.1002/pro.70050. PMID: 39969084; PMCID: PMC11837046.