Stefan Klimaj, PhD
Stefan Klimaj, PhD
I am a virologist and innate immunologist studying how viruses interact with, evade, and reshape host immune defenses. I completed my PhD at the University of New Mexico at the end of last year in the lab of Dr. Alison Kell, where my work focused on Seoul orthohantavirus replication in endothelial cells, with particular emphasis on innate immune sensing through the RIG-I-like receptor pathway and the spatial organization of viral replication. My research examined how differences in viral infection efficiency and host immune responses between human and rodent reservoir hosts contribute to divergent host immune responses, and how this could explain divergent disease outcomes. Broadly, I am interested in negative-sense RNA viruses, virus-driven cellular remodeling, and how conserved host-virus interfaces that may inform antiviral strategies. Outside the lab, I enjoy baking, board games, and exploring the city and outdoors with my senior dog Samantha and my partner Ryan.
