The Ott Lab publishes novel research on SARS-CoV-2 variants Read More

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Neutralizing antibody activity against SARS-CoV-2 variants in gestational age–matched mother-infant dyads after infection or vaccination.

Matsui Y, Li L, Prahl M, Cassidy A, Ozarslan N, Golan Y, Gonzalez V, Lin C, Jigmeddagva U, Chidboy M, Montano M, Taha T, Khalid M, Sreekumar B, Hayashi J, Chen P, Kumar G, Warrier L, Wu A, Song D, Jegatheesan P, Rai D, Govindaswami B, Needens J, Rincon M, Myatt L, Asiodu I, Flaherman V, Afshar Y, Jacoby V, Murtha A, Robinson J, Ott M, Greene W, Gaw S. Neutralizing antibody activity against SARS-CoV-2 variants in gestational age-matched mother-infant dyads after infection or vaccination. JCI Insight. 2022 . doi: 10.1172/jci.insight.157354. 

Immediate myeloid depot for SARS-CoV-2 in the human lung.

Magnen M, You R, Rao AA, Davis RT, Rodriguez L, Simoneau CR, Hysenaj L, Hu KH; UCSF COMET Consortium; Love C, Woodruff PG, Erle DJ, Hendrickson CM, Calfee CS, Matthay MA, Roose JP, Sil A, Ott M, Langelier CR, Krummel MF, Looney MR.

Res Sq [Preprint]. 2022 May 17:rs.3.rs-1639631. doi: 10.21203/rs.3.rs-1639631/v1. PMID: 35611333; PMCID: PMC9128787.

Neutralizing immunity in vaccine breakthrough infections from the SARS-CoV-2 Omicron and Delta variants.

Servellita V, Syed AM, Morris MK, Brazer N, Saldhi P, Garcia-Knight M, Sreekumar B, Khalid MM, Ciling A, Chen PY, Kumar GR, Gliwa AS, Nguyen J, Sotomayor-Gonzalez A, Zhang Y, Frias E, Prostko J, Hackett J Jr, Andino R, Wadford DA, Hanson C*, Doudna J,* Ott M*, Chiu CY*. Neutralizing immunity in vaccine breakthrough infections from the SARS-CoV-2 Omicron and Delta variants. Cell. 2022. doi: 10.1016/j.cell.2022.03.019.

Hydration for Clean Air Today.

Edwards DA, Norden B, Karnath L, Yaghi O, Roy CJ, Johanson D, Ott M, Brownstein J, Grove J, Tomson G, Friberg P  Hydration for Clean Air Today. Mol Front J. 2022. doi: 10.1142/S252973252101001X.

Identification of a therapeutic interfering particle-A single-dose SARS-CoV-2 antiviral intervention with a high barrier to resistance.

Chaturvedi S, Vasen G, Pablo M, Chen X, Beutler N, Kumar A, Tanner E, Illouz S, Rahgoshay D, Burnett J, Holguin L, Chen PY, Ndjamen B, Ott M, Rodick R, Rogers T, Smith DM, Weinberger LS. Identification of a therapeutic interfering particle-A single-dose SARS-CoV-2 antiviral intervention with a high barrier to resistance. Cell. 2021 Dec 9;184(25):6022-6036.e18. doi: 10.1016/j.cell.2021.11.004. Epub 2021 Nov 10. PMID: 34838159; PMCID: PMC8577993.

Accelerated RNA detection using tandem CRISPR nucleases.

Liu TY, Knott GJ, Smock DCJ, Desmarais JJ, Son S, Bhuiya A, Jakhanwal S, Prywes N, Agrawal S, Díaz de León Derby M, Switz NA, Armstrong M, Harris AR, Charles EJ, Thornton BW, Fozouni P, Shu J, Stephens SI, Kumar GR, Zhao C, Mok A, Iavarone AT, Escajeda AM, McIntosh R, Kim S, Dugan EJ; IGI Testing Consortium, Pollard KS, Tan MX, Ott M, Fletcher DA, Lareau LF, Hsu PD, Savage DF, Doudna JA. Accelerated RNA detection using tandem CRISPR nucleases.

doi: 10.1038/s41589-021-00842-2