Sreekumar BK, Taha TY, Ott M.
J Clin Invest. 2022 Aug 1;132(15):e161819. doi: 10.1172/JCI161819. PMID: 35912856; PMCID: PMC9337820.
Publication Category: Hepatitis
Modelling T-cell immunity against hepatitis C virus with liver organoids in a microfluidic coculture system.
Hepatitis C Virus Infects and Perturbs Liver Stem Cells.
Meyers NL, Ashuach T, Lyons DE, Simoneau CR, Erickson AL, Bouhaddou M, Nguyen TT, Khalid MM, Taha TY, Natajaran V, Baron JL, Neff N, Zanini F, Mahmoud T, Quake SR, Krogan NJ, Cooper S, McDevitt TC, Yosef N, Ott M.
bioRxiv [Preprint] 2021 October 26:10.26.465357; doi: https://doi.org/10.1101/2021.10.26.465357
A genome-wide CRISPR screen identifies UFMylation and TRAMP-like complexes as host factors required for hepatitis A virus infection.
Kulsuptrakul J, Wang R, Meyers NL, Ott M, Puschnik AS.
doi: 10.1016/j.celrep.2021.108859.
Entangled in a membranous web: ER and lipid droplet reorganization during Hepatitis C virus infection.
Meyers N, Fontaine K, Ott M. (2016)
Curr Opin Cell Biol
Membrane Flotation Assay.
Vogt DA, Ott M.
Bio Protoc. 2015 Apr 5;5(7):e1435. doi: 10.21769/bioprotoc.1435. PMID: 27540564; PMCID: PMC4987092.
A combined proteomics/genomics approach links hepatitis C virus infection with nonsense-mediated mRNA decay.
Ramage HR, Kumar GR, Verschueren E, Johnson JR, Von Dollen J, Johnson T, Newton B, Shah P, Horner J, Krogan NJ, Ott M.
doi: 10.1016/j.molcel.2014.12.028.
The hepatitis C virus core protein inhibits adipose triglyceride lipase (ATGL)-mediated lipid mobilization and enhances the ATGL interaction with comparative gene identification 58 (CGI-58) and lipid droplets.
Camus G, Schweiger M, Herker E, Harris C, Kondratowicz AS, Tsou C-L, Farese RV, Herath K, Previs SF, Roddy TP, Pinto S, Zechner R, Ott M (2014). J Biol Chem
doi: 10.1074/jbc.M114.587816. PMID: 25381252; PMCID: PMC4276846.
Evasion of superinfection exclusion and elimination of primary viral RNA by an adapted strain of hepatitis C virus.
Webster B, Ott M, Greene WC (2013). J Virol 87:13354–13369.
Lipid droplet-binding protein TIP47 regulates hepatitis C Virus RNA replication through interaction with the viral NS5A protein.
Vogt DA, Camus G, Herker E, Webster BR, Tsou C-L, Greene WC, Yen T-SB, Ott M (2013). PLoS Pathog 9:e1003302.