The Ott Lab publishes novel research on SARS-CoV-2 variants Read More

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Identification of a Therapeutic Interfering Particle — a single-administration SARS-CoV-2 antiviral intervention with a high barrier to resistance

Sonali Chaturvedi, Gustavo Vasen, Michael Pablo, Xinyue Chen, Nathan Beutler, Arjun Kumar, Elizabeth Tanner, Sylvia Illouz, Donna Rahgoshay, John Burnett, Leo Holguin, Pei-Yi Chen, Blaise Ndjamen, Melanie Ott, Robert Rodick, Thomas Rogers, David M. Smith, Leor Weinberger, Identification of a Therapeutic Interfering Particle — a single-administration SARS-CoV-2 antiviral intervention with a high barrier to resistance.
Cell, 2021, https://doi.org/10.1016/j.cell.2021.11.004.

Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant

Deng X, Garcia-Knight MA, Khalid MM, Servellita V, Wang C, Morris MK, Sotomayor-González A, Glasner DR, Reyes KR, Gliwa AS, Reddy NP, Sanchez San Martin C, Federman S, Cheng J, Balcerek J, Taylor J, Streithorst JA, Miller S, Sreekumar B, Chen PY, Schulze-Gahmen U, Taha TY, Hayashi JM, Simoneau CR, Kumar GR, McMahon S, Lidsky PV, Xiao Y, Hemarajata P, Green NM, Espinosa A, Kath C, Haw M, Bell J, Hacker JK, Hanson C, Wadford DA, Anaya C, Ferguson D, Frankino PA, Shivram H, Lareau LF, Wyman SK, Ott M, Andino R, Chiu CY.

doi: 10.1016/j.cell.2021.04.025.

SARS-CoV-2 infection studies in lung organoids identify TSPAN8 as novel mediator

Hysenaj L, Little S, Kulhanek K, Gbenedio OM, Rodriguez L, Shen A, Lone JC, Lupin-Jimenez LC, Bonser LR, Serwas NK, Bahl K, Mick E, Li JZ, Ding VW, Matsumoto S, Maishan M, Simoneau C, Fragiadakis G, Jablons DM, Langelier CR, Matthay M, Ott M, Krummel M, Combes AJ, Sil A, Erle DJ, Kratz JR, Roose JP.

doi: 10.1101/2021.06.01.446640.