Weinberg ZY, Soliman SS, Kim MS, Chen IP, Ott M, El-Samad H.
2024 Jan 15:2024.01.12.575267. doi: 10.1101/2024.01.12.575267. PMID: 38293112; PMCID: PMC10827046.
Publication Category: COVID-19 (SARS-CoV-2)
Previous exposure to Spike-providing parental strains confers neutralizing immunity to XBB lineage and other SARS-CoV-2 recombinants in the context of vaccination
Suryawanshi RK, Taha TY, McCavitt-Malvido M, Silva I, Khalid MM, Syed AM, Chen IP, Saldhi P, Sreekumar B, Montano M, Foresythe K, Tabata T, Kumar GR, Sotomayor-Gonzalez A, Servellita V, Gliwa A, Nguyen J, Kojima N, Arellanor T, Bussanich A, Hess V, Shacreaw M, Lopez L, Brobeck M, Turner F, Wang Y, Ghazarian S, Davis G, Rodriguez D, Doudna J, Spraggon L, Chiu CY, Ott M.
2023 Dec;12(2):2270071. doi: 10.1080/22221751.2023.2270071. Epub 2023 Oct 31. PMID: 37869789; PMCID: PMC10619466.
Assembly reactions of SARS-CoV-2 nucleocapsid protein with nucleic acid
Zhao H, Syed AM, Khalid MM, Nguyen A, Ciling A, Wu D, Yau WM, Srinivasan S, Esposito D, Doudna JA, Piszczek G, Ott M, Schuck P.
[Preprint]. 2023 Nov 23:2023.11.22.568361. doi: 10.1101/2023.11.22.568361. PMID: 38045338; PMCID: PMC10690241.
Colloidal aggregation confounds cell-based Covid-19 antiviral screens
Glenn IS, Hall LN, Khalid MM, Ott M, Shoichet BK.
2023 Oct 30:2023.10.27.564435. doi: 10.1101/2023.10.27.564435. PMID: 37961552; PMCID: PMC10634915.
Post-acute immunological and behavioral sequelae in mice after Omicron infection
Ma T, Suryawanshi RK, Miller SR, Ly KK, Thomas R, Elphick N, Yin K, Luo X, Kaliss N, Chen IP, Montano M, Sreekumar B, Standker L, Münch J, Damron FH, Palop JJ, Ott M, Roan NR.
Preprint]. 2023 Oct 4:2023.06.05.543758. doi: 10.1101/2023.06.05.543758. PMID: 37333294; PMCID: PMC10274741.
Mild SARS-CoV-2 infection results in long-lasting microbiota instability.
Upadhyay V, Suryawanshi RK, Tasoff P, McCavitt-Malvido M, Kumar RG, Murray VW, Noecker C, Bisanz JE, Hswen Y, Ha CWY, Sreekumar B, Chen IP, Lynch SV, Ott M, Lee S, Turnbaugh PJ.
2023 Aug 31;14(4):e0088923. doi: 10.1128/mbio.00889-23. Epub 2023 Jun 9. PMID: 37294090; PMCID: PMC10470529.
A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication and pathogenesis in vivo
Taha TY, Suryawanshi RK, Chen IP, Correy GJ, McCavitt-Malvido M, O’Leary PC, Jogalekar MP, Diolaiti ME, Kimmerly GR, Tsou CL, Gascon R, Montano M, Martinez-Sobrido L, Krogan NJ, Ashworth A, Fraser JS, Ott M.
2023 Aug 31;19(8):e1011614. doi: 10.1371/journal.ppat.1011614. PMID: 37651466; PMCID: PMC10499221.
SARS-CoV-2 protein ORF8 limits expression levels of Spike antigen and facilitates immune evasion of infected host cells
Kim IJ, Lee YH, Khalid MM, Chen IP, Zhang Y, Ott M, Verdin E.
2023 Aug;299(8):104955. doi: 10.1016/j.jbc.2023.104955. Epub 2023 Jun 23. PMID: 37354973; PMCID: PMC10289268.
Structure-Based Discovery of Inhibitors of the SARS-CoV-2 Nsp14 N7-Methyltransferase
Singh I, Li F, Fink EA, Chau I, Li A, Rodriguez-Hernández A, Glenn I, Zapatero-Belinchón FJ, Rodriguez ML, Devkota K, Deng Z, White K, Wan X, Tolmachova NA, Moroz YS, Kaniskan HÜ, Ott M, García-Sastre A, Jin J, Fujimori DG, Irwin JJ, Vedadi M, Shoichet BK.
2023 Jun 22;66(12):7785-7803. doi: 10.1021/acs.jmedchem.2c02120. Epub 2023 Jun 9. PMID: 37294077; PMCID: PMC10374283.
Mercapto-pyrimidines are reversible covalent inhibitors of the papain-like protease (PLpro) and inhibit SARS-CoV-2 (SCoV-2) replication
Bajaj T, Wehri E, Suryawanshi RK, King E, Pardeshi KS, Behrouzi K, Khodabakhshi Z, Schulze-Gahmen U, Kumar GR, Mofrad MRK, Nomura DK, Ott M, Schaletzky J, Murthy N.
2023 Jun 12;13(26):17667-17677. doi: 10.1039/d3ra01915b. PMID: 37312993; PMCID: PMC10259201.